Dampak pencemaran benzena terhadap lingkungan serta mekanismenya dalam memicu kanker: sebuah tinjauan literatur

  • Davit Aldi Program Studi Konservasi Sumber Daya Alam, Universitas Teknologi Sumbawa, Sumbawa, Indonesia
Keywords: benzene, carcinogenic, environment, metabolic, genetic

Abstract

Benzene (C6H6) is an aromatic hydrocarbon compound that is widely used in everyday life. However, the use of benzene compounds can endanger the environment and health because benzene is carcinogenic. This research was conducted to examine the negative effects of benzene as a trigger for disease and cancer. This research uses a descriptive qualitative analysis method to describe the process and negative impacts of benzene on humans and the environment. Benzene can settle in water or plants which are a source of animal feed and enter the food chain cycle, then reaches humans. Exposure to benzene, either directly or indirectly, can cause cancer in humans and animals. The direct impact of consuming food or drinks containing high levels of benzene can cause vomiting, stomach irritation, dizziness, drowsiness, seizures, rapid heart rate, coma, and death. Apart from the level of exposure, metabolic processes determined by genetics are factors that influence the impact. Humans with a high metabolic rate have a direct correlation with benzene levels in the body. The results of the paper conclude that benzene has a bad influence on living creatures which disrupts the final results of living creatures' metabolism.

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References

[ACS] American Chemical Society. 2023. Benzene [internet]. Tersedia di: https://www.acs.org/molecule-of-the-week/archive/b/benzene.html
Amstrong TW, Zaleski RT, Konkel WJ and Parkerton TJ. 2002. A tiered approach to assessing children’s exposure: a review of methods and data. Toxicology Letters 127:111-119.
Åstrand I. 1985. Uptake of solvents from the lungs. British Journal of Industrial Medicine 42:217–218.
[ATSDR] Agency for Toxic Substances and Disease Registry. 2007. Public health statement: benzene. Department of Health and Human Services. Atlanta.
Blank IH and McAuliffe DJ. Penetration of benzene through human skin. 1985. Journal of Investigative Dermatology 85(6):522-526.
Chaiklieng S, Suggaravetsiri P, Kaminski N and Autrup H. 2019. Factors
affecting urinary tt-Muconic acid detection among benzene exposed workers at gasoline stations. Internasional Journal of Environmental Research and Public Health 16(21):1-11.
Davidson RD, Courage C, Rushton L and Levy L. 2001. Benzene in the environment: an assessment of the potential risks to the health of the population. Occupational and Environmental Medicine 58(1):2–13.
Harrison R, Saborit JMD, Dor F and Henderson R. 2010. WHO guidelines for indoor air quality. World Health Organization. Geneva.
Huff J. 2007. Benzene-induced cancers: abridged history and occupational health impact. International Journal of Occupational and Environmental Health 13(2):213-221.
Irons RD. 1985. Quinones as toxic metabolites of benzene. Journal of Toxicology and Environmental Health 16(5):673-678.
Johnson ES, Langård S and Lin YS. 2007. A critique of benzene exposure in the general population. Science of the Total Environment 374(2):183-198.
Jones AY, Anderson D and Parke DV. 1991. The toxicity of benzene and its metabolism and molecular pathology in human risk assessment. British Journal of Industrial Medicine 48(7):437-444.
Kasemy ZA, Kamel GM, Abdel-Rasoul GM and Ismail AA. 2019. Environmental and health effects of benzene exposure among egyptian taxi drivers. Hindawi Journal of Environmental and Public Health 2019(7):1-6.
Kirkeleit J, Riise T, Gjertsen BT, Moen BE, Bråtveit M and Bruserud Ø. 2008. Effects of benzene on human hematopoiesis. The Open Hematology Journal 2:87-102.
Marchetti F, Brenda E, Weldon RH, Li G, Zhang L, Rappaport SM, Schmid TE, Xing C, Kurtovich E and Wyrobek AJ. Occupational exposure to benzene and chromosomal structural aberrations in the sperm of Chinese men. Environmental Health Perspectives 120(2):229-234.
McHale C, Zhang L and Smith MT. 2011. Current understanding of the mechanism of benzene-induced leukemia in humans: implications for risk assessment. Carcinogenesis 33(2):240-252.
Neri M, Ugolini D, Bonassi S, Fucic A, Holland N, Knudsen LE, Sram RJ, Ceppi M and Bocchini V. 2006. Children’s exposure to environmental pollutants and biomarkers of genetic damage. II. Results of a comprehensive literature search and meta-analysis. Mutation Research 612(1):14–39.
PerMenNaKer (Peraturan Menteri Tenaga Kerja dan Transmigrasi) Nomor 13 Tahun 2011 tentang nilai ambang batas nilai ambang batas faktor fisika dan faktor kimia di tempat kerja.
Santos VPSd , Salgado AM, Torres AG and Pereira KS. 2015. Benzene as a chemical hazard in processed foods. International Journal of Food Science 2015:1-7.
Smith MT. 1996. Overview of benzene-induced aplastic anaemia. European Journal of Haematology 57(S60):107-110.
Ukoha PO, Ekere NR, Timothy CL and Agbazue VE. 2015. Benzene, Toluene, Ethylybenzene and Xylenes (Btex) contamination of soils and water bodies from alkyd resin and lubricants industrial production plant. Journal of Chemical Society of Nigeria 40(1):51-55.
Utomo S. 2012. Bahan berbahaya dan beracun (B-3) dan keberadaannya di dalam limbah. Jurnal Konversi 1(1):37-46.
Witz G, Zhang Z and Goldstein BD. 1996. Reactive ring-opened aldehyde metabolites in benzene hematotoxicity. Environtal Health Perspectives 4(6):1195-1199.
Zhang L, Eastmond DA and Smith MT. 2002. The nature of chromosomal aberrations detected in humans exposed to benzene. Critical Reviews in Toxicology 32(1):1-42.
Zhang L, Rothman N, Wang Y, Hayes RB , Bechtold W, Venkatesh P, Yin S, Wang Y, Dosemeci M, Li G, Lu W and Smith MT. 1996. Interphase cytogenetics of workers exposed to benzene. Environmental Health Perspectives 104(6):1325-1329.
Ziółkowska A and Wyszkowski M. 2010. Toxicity of petroleum substances to microorganisms and plants. Ecological Chemistry And Engineering S 17(1):73-82.
Published
2024-04-30
How to Cite
Aldi, D. (2024). Dampak pencemaran benzena terhadap lingkungan serta mekanismenya dalam memicu kanker: sebuah tinjauan literatur. Jurnal Pengelolaan Lingkungan Berkelanjutan (Journal of Environmental Sustainability Management), 8(1), 87-98. https://doi.org/https://doi.org/10.36813/jplb.8.1.87-98
Section
Articles